So, you decided to enter the CAM facility. As soon as you walk in and see the egg incubators you remember what your colleague told you. CAM refers to the ChorioAllantoic Membrane. It is a highly vascularized membrane that develops during embryogenesis in fertilized chicken eggs. It is a model to study blood vessel growth but your colleague also uses it to study tumor growth and drug toxicity. Perhaps you can read some background on it in the Auditorium but for now, you immediately see an opportunity for your research. Using the CAM model would be an easy and cheap way to test the toxicity of your compounds.
Unfortunately, when you check the egg incubators you notice that they are already filled with eggs. Apparently, somebody is already performing an assay and there is no more space for additional eggs. But, as it appears to be your lucky day, on top of the incubator you find a note.
To whom it may concern,
Attached, please find the results of an experiment that I did last week. To check whether the CAM model was suitable for my study, I performed a toxicity test combining radiotherapy with some random compounds that I took out of the fridge. It appears that the experiment worked and that I can use the model for my research. However, I do not need the results that were generated in this pilot. So feel free to take these data if you can use them. Just make sure you discard the eggs before they hatch...
A fellow researcher
Could it really be your lucky day? If this colleague accidentally included your compounds in this pilot test you could readily look at the toxicity data. Then you only have to detemine the effects on tumor growth inhibition. First, you discard the eggs from they incubator and then decide to check the datafile. It was a smart move to check the CAM facility, hopefully you are just as lucky in the Animal facility.
Analyze the toxicity data. Together with tumor growth data from the Animal facility you might be able to select the best compound.